Recent Publications
Technology and Innovation Resources
Review publications from BioMADE-funded projects on topics like technology and innovation, safety and security, and thought leadership pieces.
Photos: © Amyris; IBRL - Taylor Meredith
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Astolfi, M. C. T., Yoder, S. D., Delfa-Lalaguna, M., Winegar, P. H., Holm, S. K. F., Lei, M., Zhao, X., Tan, S. E., Louie, R., Hillson, N. J., Hudson, G. A., & Keasling, J. D. (2025). Automated strain construction for biosynthetic pathway screening in yeast. ACS Synthetic Biology, 14(10), 4143–4151. https://doi.org/10.1021/acssynbio.5c00554
Chen, X. (2023). Enabling chemoenzymatic strategies and enzymes for synthesizing Sialyl glycans and Sialyl glycoconjugates. Accounts of Chemical Research, 57(2), 234–246. https://doi.org/10.1021/acs.accounts.3c00614
Crowe, S. A., Liu, Y., Zhao, X., Scheller, H. V., & Keasling, J. D. (2024). Advances in engineering nucleotide sugar metabolism for natural product glycosylation in saccharomyces cerevisiae. ACS Synthetic Biology, 13(6), 1589–1599. https://doi.org/10.1021/acssynbio.3c00737
Crowe, S. A., Zhao, X., Gan, F., Chen, X., Hudson, G. A., Astolfi, M. C., Scheller, H. V., Liu, Y., & Keasling, J. D. (2024). Engineered Saccharomyces cerevisiae as a Biosynthetic Platform of Nucleotide Sugars. ACS Synthetic Biology, 13(4), 1215–1224. https://doi.org/10.1021/acssynbio.3c00666
Han, Z., Guo, A. X., Luo, T., Cai, T., & Mirkin, C. A. (2025). Biomineralization of semiconductor quantum dots using DNA-functionalized protein nanoreactors. Science Advances, 11(19). https://doi.org/10.1126/sciadv.adv6906
Huang, J., Wang, Z., Liang, J., Li, X.-Y., Pietryga, J., Ye, Z., Smith, P. T., Kulaksizoglu, A., McCormick, C. R., Kim, J., Peng, B., Liu, Z., Xie, K., Torrisi, S. B., Montoya, J. H., Wu, G., Sargent, E. H., & Mirkin, C. A. (2025). Accelerating the pace of oxygen evolution reaction catalyst discovery through Megalibraries. Journal of the American Chemical Society, 147(34), 30956–30966. https://doi.org/10.1021/jacs.5c08326
Kim, N., Lee, J., & Su, X. (2023). Precision tuning of highly selective polyelectrolyte membranes for redox‐mediated electrochemical separation of organic acids. Advanced Functional Materials, 33(12). https://doi.org/10.1002/adfm.202211645
Kulaksizoglu, A., Wahl, C. B., Xu, D. D., Guo, A. X., Liu, Y., McCormick, C. R., dos Reis, R., Dravid, V. P., & Mirkin, C. A. (2025). Discovering complex metal chalcogenide nanostructures through nanoreactor-mediated synthesis. Journal of the American Chemical Society, 148(1), 1692–1702. https://doi.org/10.1021/jacs.5c18834
Kuo, M.-T., & Reuel, N. F. (2025). Resolving the kinetics of single-walled carbon nanotube–polyester polyurethane nanoparticle conjugate fluorescence sensors toward polymer degrading enzymes. Nano Letters, 25(2), 715–721. https://doi.org/10.1021/acs.nanolett.4c04964
Liu, Y., Zhao, X., Gan, F., Chen, X., Deng, K., Crowe, S. A., Hudson, G. A., Belcher, M. S., Schmidt, M., Astolfi, M. C., Kosina, S. M., Pang, B., Shao, M., Yin, J., Sirirungruang, S., Iavarone, A. T., Reed, J., Martin, L. B., El-Demerdash, A., … Keasling, J. D. (2024). Complete biosynthesis of QS-21 in engineered yeast. Nature, 629(8013), 937–944. https://doi.org/10.1038/s41586-024-07345-9
Meyersohn, M. S., Block, A., Bates, F. S., & Hillmyer, M. A. (2024). Tackling the thermodynamic stability of low-ceiling temperature polymers for the preparation of tough and chemically recyclable thermoplastic polyurethane-urea elastomers. Macromolecules, 57(19), 9230–9240. https://doi.org/10.1021/acs.macromol.4c01431
Ophir, Y., Wong, J. H., Haddad, K. R., Huuskonen, A., Karmaker, A., Gore, V., Jung, S., Oloumi, A., Liu, Y., Fu, J., Zhang, L., Huang, P., Minami, S. A., Garimella, S. S., Thyagatur, A., Zaini, P. A., Vitikainen, M., Tchelet, R., Valbuena, N., ... Nandi, S. (2025). Expression and characterization of SARS-CoV-2 spike protein in Thermothelomyces heterothallica C1. Vaccine, 65, Article 127784. https://doi.org/10.1016/j.vaccine.2025.127784
Quezada, A., Annapareddy, A., Javanmardi, K., Cooper, J., & Finkelstein, I. J. (2024). Mammalian antigen display for pandemic countermeasures. Methods in Molecular Biology, 191–216. https://doi.org/10.1007/978-1-0716-3666-4_12
San Martín R, Liu Y, Yang Y, Fox CB, Iyer LR, Mohamath R, Ramer-Denisoff G, Kinsey R, Guderian JA, Schwabach J, Deng S, Fernandes NAT and Radke C (2026) Structure and immunological activity of QS-21 variant from Quillaja saponaria aerial biomass. Front. Immunol. 17:1771912. doi: 10.3389/fimmu.2026.1771912
Shin, Donghoon, et al. “A-cation-dependent structure–optical property relationships of halide perovskite heterostructures with complex interfaces.” Journal of the American Chemical Society, 9 Oct. 2025, https://doi.org/10.1021/jacs.5c10848
Thomas, J., Bouscher, R. F., Nwosu, J., & Soucek, M. D. (2022). Sustainable thermosets and composites based on the epoxides of norbornylized seed oils and biomass fillers. ACS Sustainable Chemistry & Engineering, 10(37), 12342–12354. https://doi.org/10.1021/acssuschemeng.2c03434
Thomas, J., Nwosu, J., & Soucek, M. D. (2023c). Sustainable biobased composites from norbornylized linseed oil and biomass sorghum fillers. Composites Communications, 42, 101695. https://doi.org/10.1016/j.coco.2023.101695
Thomas, J., Nwosu, J., & Soucek, M. D. (2023b). Acid-cured norbornylized seed oil epoxides for sustainable, recyclable, and reprocessable thermosets and composite application. ACS Applied Polymer Materials, 5(3), 2230–2242. https://doi.org/10.1021/acsapm.2c02225
Tran, V. G., Mishra, S., Bhagwat, S. S., Shafaei, S., Shen, Y., Allen, J. L., Crosly, B. A., Tan, S.-I., Fatma, Z., Rabinowitz, J. D., Guest, J. S., Singh, V., & Zhao, H. (2023). An end-to-end pipeline for succinic acid production at an industrially relevant scale using Issatchenkia orientalis. Nature Communications, 14(1). https://doi.org/10.1038/s41467-023-41616-9
Wang, Zhe, et al. “Polyelemental nanoparticle synthesis enabled by noncontact metallothermic reactions.” Journal of the American Chemical Society, vol. 147, no. 40, 26 Sept. 2025, pp. 36669–36676, https://doi.org/10.1021/jacs.5c12003
Zaini, P. A., Haddad, K. R., Feinberg, N. G., Ophir, Y., Nandi, S., McDonald, K. A., & Dandekar, A. M. (2024). Leveraging walnut somatic embryos as a biomanufacturing platform for recombinant proteins and metabolites. BioTech, 13(4), 50. https://doi.org/10.3390/biotech13040050
Zhang, L., Li, Y., Li, R., Yang, X., Zheng, Z., Fu, J., Yu, H., & Chen, X. (2023). Glycoprotein in vitro n-glycan processing using enzymes expressed in E. coli. Molecules, 28(6), 2753. https://doi.org/10.3390/molecules28062753
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Attal-Juncqua, A., Dods, G., Crain, N., Diggans, J., Dodds, D., Evans, S., Fackler, N., Flyangolts, K., Gibson, K., Kosal, M. E., Kunjapur, A., Read, R., Renda, B., Scown, C. D., Tchedre, K., Ternus, K., Vitalis, B., & Gronvall, G. (2024). Shaping the future US bioeconomy through safety, security, sustainability, and social responsibility. Trends in Biotechnology, 42(6), 671–673. https://doi.org/10.1016/j.tibtech.2023.11.015
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Rose, P. P., & Friedman, D. (2021). Bioinspired, BioDriven, BioMADE: The U.S. bioindustrial manufacturing and design ecosystem as a driver of the 4th industrial revolution. Engineering Biology, 5(3), 60–63. https://doi.org/10.1049/enb2.12014
Smanski, M. J., Aristidou, A., Carruth, R., Erickson, J., Gordon, M., Kedia, S. B., Lee, K. H., Prather, D., Schiel, J. E., Schultheisz, H., Treynor, T. P., Evans, S. L., Friedman, D. C., & Tomczak, M. (2022). Bioindustrial Manufacturing Readiness Levels (BioMRLs) as a shared framework for measuring and communicating the maturity of bioproduct manufacturing processes. Journal of Industrial Microbiology and Biotechnology, 49(5). https://doi.org/10.1093/jimb/kuac022
Tomczak M, and Norquist, P. Shaping Future Supple Chains with Bioindustrial Manufacturing. The Bridge 55:2 42-47 (2025). https://www.nae.edu/19579/19582/21020/338895/338972/Shaping-Future-Supply-Chains-with-Bioindustrial-Manufacturing
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